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Delirium

Delirium is also known as an Acute Confusional State. It presents with an acute and fluctuating course of changes in cognitive function, perception, physical function and social behaviour:

  • Disorientation

  • Hallucinations

  • Inattention

  • Memory problems

  • Change in mood or personality

  • Disturbed sleep

  • Hypoactivity

  • Reversed sleep-wake cycle


Risk factors - Elderly, Dementia, Severe illness, Hip fracture


Causes - Infection, Pain, Post-surgery, Metabolic, Medication, Neurological, Environment


Types - Hyperactive, Mixed, Hypoactive

  • Hypoactive is the most common type, but is

    easily mistaken for depression/dementia


Investigations:

  • Cognitive screening tests - Short-CAM, 4AT, or DSM-5

  • Delirium screen - Glucose, Calcium, Vitamin B12, Folate, TSH, MSU, CTH

  • Infection screen - Urine dip, CXR, Blood culture


Management:

  • Treat underlying cause

  • Small doses of haloperidol or olanzapine may be considered



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