Triple Assessment of a Breast Lump
The triple assessment includes Clinical, Imaging, Histology.
Imaging:
Mammography - Used in older pts (35+ years) - Identifies microcalcifications and more dense tissue
USS - Used in younger pts (< 35 years) as their breast tissue is too dense for a mammography - Identifies solid, cystic lesions

Histology - Done by Fine Needle Aspiration (FNA) or Core Biopsy. The numbering system - FNA is ‘C’, Biopsy is ‘B’:
C1/B1 - Inadequate or not diagnostic
C2/B2 - Benign breast disease
C3/B3 - Ambiguous, points more to Benign
C4/B4 - Ambiguous, points more to Malignant
C5/B5 - Malignant
Breast lumps are most likely to be a Fibroadenoma or Fibrocystic change in younger women, or Breast cancer in older women.
When to refer:
30+ years w/new unexplained breast lump = Urgent referral
< 30 years w/new unexplained breast lump = Routine referral