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Eating Disorders

Anorexia Nervosa

BMI < 17.5. They tend to carry out behaviours that leads to weight loss, including:

  • Dietary restriction

  • Over-activity

  • Self-induced Vomiting

  • Laxative misuse

  • Diuretic misuse


A key characteristic that these patients have is Psychopathology; an irrational fear (phobia) of a normal body weight.


Clinical Features

  • Endocrine dysfunction – Low Sex hormone levels (FSH/LH/Oestrogen/Testosterone), Secondary Amenorrhoea, Menstrual irregularity, Loss of libido

  • Hypotension

  • Bradycardia

  • Hypokalaemia

  • Cardiac complications – Arrhythmia, Cardiac atrophy

    • In anorexic patients, their body begins to take muscle from many organs for energy e.g. heart, gut (Constipation), muscle

  • Osteoporosis

  • Lanugo hair (fine hair covering skin)

  • Mood changes, anxiety, depression


Severe and Enduring Anorexia (SE-AN):

After 7 years, the anorexia becomes:

  • Persistent – If starvation is less marked, the psychopathology remains, w/o any periods of remission of psychopathology

  • Resistant to change

  • Severe – Mixed feelings about change, Ego-synchronically attached to low weight, and Behaviour/beliefs/emotions are in harmony with the illness and not reality


Management:

  • Aim is to get back to a normal weight. However, the intake shouldn’t be resumed too quickly as it can lead to Refeeding syndrome – Rapidly increasing insulin leads to shifts of potassium, magnesium and phosphate into cells.


Bulimia Nervosa

Differs from Anorexia Nervosa as patients:

  • Often have a normal BMI – body weight tends to fluctuate

  • Lack of Psychopathology i.e. no irrational fear of normal body weight

  • Has a later onset


It's highly associated with PCOS.


Clinical Features:

  • Binge-eating - Eating binge foods very quickly whether hungry or not and person eats in a “dazed state” – They eat to a point of being uncomfortably full

  • Purging – Patient wants to undo all the “damage” from their binge via vomiting, laxatives, diuretics, fasting• Normal weight but major fluctuations

  • Low self-esteem

  • Self-evaluation unduly influenced by body-shape & weight (BUT no phobia)

  • Lack of control

  • Anger, anxiety & depression


Physical features:

  • Teeth erosion, Alkalosis, Mouth ulcers, Swollen salivary glands – Due to recurrent vomiting

  • Russell’s sign – Calluses of knuckles where they’ve been scraped across teeth to induce vomiting

  • Gastro-oesophageal reflux and irritation

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Russell's Sign on the knuckles of the index and ring fingers - Kyukyusha - https://commons.wikimedia.org/wiki/File:Russell%27s_Sign.png

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