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Eczema

This is also known as atopic dermatitis, which is a chronic atopic condition causing defects in the natural continuity of the skin barrier, therefore leading to inflammation. The pathophysiology of it includes:

  • Defects in the skin barrier to form tiny gaps, allowing for irritants, allergens, and microbes to enter the skin

  • Immune response to these leads to the inflammation and associated symptoms


Presentation

Dry skin and flares of itchy, erythematous, poorly demarcated patches

  • Usually forms on the cheeks of infants

  • Usually forms on the flexural surfaces in older children and adults

“Inflamed atopic dermatitis on the abdomen and the left thigh of a 2 months old child.” © Gzzz CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0/)

Complications

  • Eczema herpeticum - Dermatological emergency where the impaired skin protection leads to a disseminated HSV infection. Presents as a monomorphic vesicular rash, which can ulcerate and crust. Treated with IV Aciclovir.

  • Superficial bacterial infection - usually caused by staph or strep

  • Erythroderma - dermatological emergency where there is widespread erythema affecting >90% of the skin surface, which can result in heat and fluid loss, causing hypothermia and systemic symptoms

  • Side-effects of long-term topical corticosteroid use - skin thinning, striae, telangiectasia


Management

Advise patients to avoid:

  • Activities that break down the skin barrier e.g. hot baths, itching, scrubbing skin, and using soaps that remove natural oils of the skin

  • Known triggers e.g. humidity, diet etc.


Things to give:

  • Emollients - thick, greasy creams e.g. E45, Cetraben to help create an artificial skin barrier

  • Topical corticsteroids e.g. Hydrocortisone, Betamethasone (Betnovate)



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