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Prematurity

Prematurity is defined as foetus that is delivered < 37 weeks. It's classified into:

  • Extreme prematurity - < 28 weeks

  • Very prematurity - 28-32 weeks

  • Moderate to late prematurity - 32-37 weeks


Risk factors:

  • Smoking

  • Alcohol

  • Drugs

  • Overweight/Underweight mother

  • Multiple pregnancies

  • Hx of prematurity


Management

It's very important to delay labour if possible in these situations as each extra week of gestation has a HUGE improvement on prognosis. This can be done prophylactically (before labour starts) with:

  • Vaginal progesterone – Suppository put in vagina to discourage labour

  • Cervical cerclage – Suture cervix to hold it closed

“Illustration showing a cervical cerclage” © BruceBlaus CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0/)

If premature labour is suspected/confirmed, options include:

  • Tocolysis with Nifedipine – Suppresses labour

  • Maternal corticosteroids – Improve surfactant production and lung development to reduce risk/severity of respiratory distress upon delivery

  • IV Magnesium Sulphate – Protects baby’s brain


  • Delayed cord clamping or cord milking


Complications


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