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Reactive Arthritis

This is also known as Reiter’s syndrome. It's a mono-arthritis, typically occurring after a preceding STI or gastroenteritis. The most common preceding infections are Chlamydia, Shigella, and Salmonella.


Risk factors - Male, HLA-B27 +ve


Presentation - "Can't see, Can't pee, Can't climb a tree"

  • "Can't see" = Conjunctivitis - discharge, erythema, burning, photophobia

  • "Can't pee" = Urethritis - dysuria, urgency, frequency, discharge

  • "Can't climb a tree" = Arthritis - pain, swelling in knee/ankle/foot


An important differential here is Septic Arthritis (The joint in reactive arthritis doesn't contain any infection itself, so joint aspiration will be negative).


Management

  • Exclude Septic Arthritis! - Joint aspiration and MC&S

  • NSAIDs, Steroids

  • Most resolve within 6 months



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